8fg2

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SARS-CoV-2 Nucleocapsid dimer structure determined from COVID-19 patientsSARS-CoV-2 Nucleocapsid dimer structure determined from COVID-19 patients

Structural highlights

8fg2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NCAP_SARS2 Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.

8fg2, resolution 6.00Å

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OCA