Crystal structure of the mutant F100A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMPCrystal structure of the mutant F100A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP

Structural highlights

3nqa is a 2 chain structure with sequence from "methanobacterium_thermoautotrophicus"_(sic)_zeikus_and_wolfe_1972 "methanobacterium thermoautotrophicus" (sic) zeikus and wolfe 1972. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:pyrF, MTH_129 ("Methanobacterium thermoautotrophicus" (sic) Zeikus and Wolfe 1972)
Activity:Orotidine-5'-phosphate decarboxylase, with EC number 4.1.1.23
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]

See Also

3nqa, resolution 1.40Å

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OCA