3mdb
Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4
Structural highlights
Function[KI13B_HUMAN] Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.[1] [ADAP1_HUMAN] GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).[2] [3] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Human
- Arrowsmith, C H
- Bochkarev, A
- Bountra, C
- Edwards, A M
- MacKenzie, F
- Park, H
- Structural genomic
- Shen, L
- Tempel, W
- Tong, Y
- Weigelt, J
- Atp-binding
- Cytoskeleton
- Gap
- Gtpase activation
- Kinesin
- Metal-binding
- Microtubule
- Motor protein
- Nucleotide-binding
- Nucleus
- Phosphoprotein
- Sgc
- Transport protein-hydrolase activator complex
- Zinc-finger