2r4h
Crystal structure of a C1190S mutant of the 6th PDZ domain of human membrane associated guanylate kinaseCrystal structure of a C1190S mutant of the 6th PDZ domain of human membrane associated guanylate kinase
Structural highlights
Function[MAGI1_HUMAN] May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Human
- Large Structures
- Arrowsmith, C H
- Cooper, C
- Delft, F von
- Doyle, D A
- Edwards, A M
- Elkins, J M
- Hozjan, V
- Kavanagh, K L
- Oppermann, U
- Pike, A C.W
- Pilka, E S
- Structural genomic
- Sundstrom, M
- Ugochukwu, E
- Weigelt, J
- Atp-binding
- Cell junction
- Membrane associated guanylate kinase
- Nucleotide-binding
- Pdz
- Phosphorylation
- Sgc
- Tight junction
- Transferase