1xi3

Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001

Structural highlights

1xi3 is a 2 chain structure with sequence from Atcc 43587. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	, ,
Gene:	thiE (ATCC 43587)
Activity:	Thiamine-phosphate diphosphorylase, with EC number 2.5.1.3
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[THIE_PYRFU] Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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OCA