Drosophila Melanogaster Cycle W398A PAS-B with Bound GlycerolDrosophila Melanogaster Cycle W398A PAS-B with Bound Glycerol

Structural highlights

5f69 is a 1 chain structure with sequence from Drome. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:cyc, CG8727 (DROME)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CYCL_DROME] Putative transcription factor involved in the generation of biological rhythms. Activates cycling transcription of Period (PER) and Timeless (TIM) by binding to the E-box (5'-CACGTG-3') present in their promoters.

5f69, resolution 1.37Å

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OCA