Hepatocyte growth factor receptor 3D structures

3D Structures of hepatocyte growth factor receptor3D Structures of hepatocyte growth factor receptor

Updated on 30-August-2021

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• Hepatocyte growth factor receptor ; Domains – α chain 125-311; SEMA 25-564; ψ 519-562; Ig1, Met741 565-740;tyrosine kinase 1041-1378
  • 1ssl – hHGFR ψ domain – human - NMR
    
  • 3q6u, 2g15 – hHGFR tyrosine kinase domain
    
  • 3dkc, 3dkf, 3dkg, 1r1w – hHGFR tyrosine kinase domain (mutant)
    
  • 7ocl, 7ocm – hHGFR α chain
    
• HGFR complex
  • 7mo7, 7mo8, 7mo9, 7moa, 7mob – hHGFR + hHGF – Cryo EM
    
  • 1r0p – hHGFR tyrosine kinase domain (mutant) + K-252A
    
  • 2uzx, 2uzy – hHGFR SEMA, ψ, Ig1, Met741 domains + internalin B
    
  • 6gcu – hHGFR SEMA, ψ, Ig1, Met741 domains + internalin B + darpin
    
  • 2rfn, 2rfs, 3ccn, 3cd8, 3f66, 2wd1, 2wgj, 3l8v, 3lq8, 2wkm, 3q6w, 3rhk, 3qti, 3zxz, 3zze, 3r7o, 3u6h, 3u6i, 4deg, 4deh, 4dei, 4aoi, 4ap7, 4gg5, 4gg7, 4eev, 4knb, 4mxc, 4r1v, 4r1y, 4xmo, 4xyf, 5dg5, 5eob, 5eyc, 5eyd, 5hni, 5hti, 5t3q, 5uab, 5uad, 6ubw, 5ya5, 6ubw, 7b3q, 7b3t, 7b3v, 7b3w, 7b3z, 7b40, 7b41, 7b42, 7b43, 7b44 – hHGFR tyrosine kinase domain + inhibitor
    
  • 3c1x, 3cth, 3ctj, 3ce3, 3efj, 3efk, 3f82, 3i5n, 3a4p, 5hlw, 5ho6, 5hoa, 5hor, 6sdd – hHGFR tyrosine kinase domain (mutant) + inhibitor
    
  • 6sd9, 6sde – hHGFR tyrosine kinase domain + cancer drug
    
  • 6sdc – hHGFR tyrosine kinase domain (mutant) + cancer drug
    
  • 1shy – hHGFR SEMA and ψ domain + hHGF β chain
    
  • 4o3t, 4o3u – hHGFR SEMA and ψ domain (mutant) + hHGF α chain (mutant) + zymogen activator peptide
    
  • 3vw8, 3zbx, 3zc5, 3zcl, 4iwd - hHGFR tyrosine kinase domain + inhibitor
    
  • 6i04, 6wvz – hHGFR SEMA domain + antibody
    
  • 5lsp – hHGFR ψ, Ig1, Met741 domains + antibody