Crystal structure of Saccharomyces cerevisiae OMP synthase in complex with PRP(CH2)PCrystal structure of Saccharomyces cerevisiae OMP synthase in complex with PRP(CH2)P

Structural highlights

4wml is a 1 chain structure with sequence from Baker's yeast. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:URA5, PYR5, YML106W, YM8339.13 (Baker's yeast)
Activity:Orotate phosphoribosyltransferase, with EC number 2.4.2.10
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PYRE_YEAST] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).[HAMAP-Rule:MF_01208]

4wml, resolution 1.73Å

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OCA