3sm9
Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonistCrystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist
Structural highlights
Function[GRM3_HUMAN] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.[1] References |
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Human
- Arrowsmith, C H
- Bountra, C
- Cossar, D
- Crombet, L
- Dobrovetsky, E
- Dong, A
- Edwards, A M
- Khutoreskaya, G
- Structural genomic
- Seitova, A
- Weigelt, J
- Wernimont, A K
- Cell membrane
- G-protein coupled receptor
- Glycoprotein
- Membrane
- Olfaction
- Phosphoprotein
- Receptor
- Sensory transduction
- Sgc
- Signaling protein
- Transducer
- Transmembrane
- Transmembrane helix