3ndv

Crystal structure of the N-terminal beta-aminopeptidase BapA in complex with ampicillinCrystal structure of the N-terminal beta-aminopeptidase BapA in complex with ampicillin

Structural highlights 3ndv is a 4 chain structure with sequence from Ccug 52537. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: , , Related: 3n2w, 3n33, 1b65 Gene: bapA (CCUG 52537) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [BAPA_SPHXN] Beta-aminopeptidase that can cleave synthetic beta-peptides which consist of backbone-elongated beta-amino acid residues that are not processed by common proteolytic enzymes. Can cleave the beta-peptides beta-homoVal-beta-homoAla-beta-homoLeu and beta-homoAla-beta-homoLeu. Requires a beta-amino acid at the N-terminus of peptide substrates and cleaves the peptide bond between the N-terminal beta-amino acid and the amino acid at the second position of tripeptidic substrates of the general structure H-betahXaa-Ile-betahTyr-OH according to the following preferences with regard to the side chain of the N-terminal beta-amino acid: aliphatic and aromatic > OH-containing > hydrogen, basic and polar. See Also Aminopeptidase

spinqualitylabelsall models 3ndv, resolution 1.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image