Crystal structure of RuvC from Pseudomonas aeruginosaCrystal structure of RuvC from Pseudomonas aeruginosa

Structural highlights

6lw3 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Activity:Crossover junction endodeoxyribonuclease, with EC number 3.1.22.4
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[A0A0C7D4E1_PSEAI] Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.[HAMAP-Rule:MF_00034][SAAS:SAAS01093222]

6lw3, resolution 2.38Å

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OCA