3b84

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Crystal structure of the human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3)Crystal structure of the human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3)

Structural highlights

3b84 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:ZBTB48, HKR3 (HUMAN)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[ZBT48_HUMAN] Binds to and regulates the J and/or S elements in MHC II promoter.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Sugawara M, Scholl T, Ponath PD, Strominger JL. A factor that regulates the class II major histocompatibility complex gene DPA is a member of a subfamily of zinc finger proteins that includes a Drosophila developmental control protein. Mol Cell Biol. 1994 Dec;14(12):8438-50. PMID:7969177

3b84, resolution 1.74Å

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