Structure Of Human ADP-Ribosylation Factor-Like 10CStructure Of Human ADP-Ribosylation Factor-Like 10C

Structural highlights

2al7 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:ARL10C (HUMAN)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[ARL8B_HUMAN] May play a role in lysosome motility (PubMed:16537643). May play a role in chromosome segregation (PubMed:15331635).[1] [2]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Okai T, Araki Y, Tada M, Tateno T, Kontani K, Katada T. Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation. J Cell Sci. 2004 Sep 15;117(Pt 20):4705-15. Epub 2004 Aug 25. PMID:15331635 doi:http://dx.doi.org/10.1242/jcs.01347
  2. Hofmann I, Munro S. An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility. J Cell Sci. 2006 Apr 15;119(Pt 8):1494-503. Epub 2006 Mar 14. PMID:16537643 doi:http://dx.doi.org/jcs.02958

2al7, resolution 1.85Å

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