Crystal structure of human GDP-D-mannose 4,6-dehydrataseCrystal structure of human GDP-D-mannose 4,6-dehydratase

Structural highlights

1t2a is a 4 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:GMDS (HUMAN)
Activity:GDP-mannose 4,6-dehydratase, with EC number 4.2.1.47
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[GMDS_HUMAN] Conversion of GDP-D-mannose to GDP-4-keto-6-D-deoxymannose.

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1t2a, resolution 1.84Å

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OCA