6itk

Crystal strcuture of malate dehydrogenase from Corynebacterium glutamicum ATCC 13032 in complex with NAD and malateCrystal strcuture of malate dehydrogenase from Corynebacterium glutamicum ATCC 13032 in complex with NAD and malate

Structural highlights

6itk is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	,
Activity:	Malate dehydrogenase, with EC number 1.1.1.37
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[MDH_CORGL] Catalyzes the reversible oxidation of malate to oxaloacetate. Exhibits higher catalytic efficiency for oxaloacetate reduction than for malate oxidation in vitro. Almost equally active both for NADH and NADPH on the bases of the kcat values at pH 6.5, but catalytic efficiency for oxaloacetate reduction is 50-fold higher with NADH.^[1]

References

↑ Genda T, Nakamatsu T, Ozak H. Purification and characterization of malate dehydrogenase from Corynebacterium glutamicum. J Biosci Bioeng. 2003;95(6):562-6. PMID:16233457

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OCA

[1] Genda T, Nakamatsu T, Ozak H. Purification and characterization of malate dehydrogenase from Corynebacterium glutamicum. J Biosci Bioeng. 2003;95(6):562-6. PMID:16233457

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