6ofc

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Crystal structure of M. tuberculosis glutamine-dependent NAD+ synthetase complexed with Sulfonamide derivative 1, pyrophosphate, and glutamineCrystal structure of M. tuberculosis glutamine-dependent NAD+ synthetase complexed with Sulfonamide derivative 1, pyrophosphate, and glutamine

Structural highlights

6ofc is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , ,
Activity:NAD(+) synthase (glutamine-hydrolyzing), with EC number 6.3.5.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[NADE_MYCTO] Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.[HAMAP-Rule:MF_02090]

6ofc, resolution 3.14Å

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