ATPase is an enzyme which catalyzes the breakdown of ATP into ADP and a phosphate ion. This dephosphorylation releases energy which the enzyme uses to drive other reactions. ATPase types include:

  • F-ATPase - the prime producers of ATP. For details see Alice Clark/ATPsynthase;
  • V-ATPase or Vacuolar-type H+ ATPase couples the energy to proton transport across membranes. For details see V-ATPase;
  • A-ATPase are found in archaea. For details see A-ATP Synthase;
  • P-ATPase transport ions;
  • E-ATPase hydrolyze extracellular ATP.
  • MipZ is an ATPase which forms a complex with the chromosome partitioning protein ParB and is responsible for the regulation of FtsZ ring formation.

ATPase domains include metal-binding domain (MBD) and nucleotide-binding domain (NBD). For more details see:



An ATPase, Human RuvB-like 1 dodecamer complex with ADP (PDB code 2c9o)

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3D Printed Physical Model of ATP Synthase3D Printed Physical Model of ATP Synthase

Shown below is a 3D printed physical model of the Respiration Electron Transport Chain. Complex I is colored red, complex II is purple, complex III is green, complex IV is blue and the atp synthase protein is colored orange, yellow and red.  


The MSOE Center for BioMolecular ModelingThe MSOE Center for BioMolecular Modeling

 

The MSOE Center for BioMolecular Modeling uses 3D printing technology to create physical models of protein and molecular structures, making the invisible molecular world more tangible and comprehensible. To view more protein structure models, visit our Model Gallery.

3D Structures of ATPase3D Structures of ATPase

ATPase 3D structures

ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Jaime Prilusky, Michal Harel, Wayne Decatur, Mark Hoelzer, Karsten Theis