Crystal structure of Mycobacterium tuberculosis BioACrystal structure of Mycobacterium tuberculosis BioA

Structural highlights

6ge8 is a 2 chain structure with sequence from "mycobacterium_muris"_smith_and_conant_in_smith_et_al._1948 "mycobacterium muris" smith and conant in smith et al. 1948. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:bioA, RN08_1757 ("Mycobacterium muris" Smith and Conant in Smith et al. 1948)
Activity:Adenosylmethionine--8-amino-7-oxononanoate transaminase, with EC number 2.6.1.62
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[A0A120IWN6_MYCTX] Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor.[HAMAP-Rule:MF_00834]

6ge8, resolution 1.87Å

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OCA