6rj2
Crystal structure of PHGDH in complex with compound 40Crystal structure of PHGDH in complex with compound 40
Structural highlights
Disease[SERA_HUMAN] Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:601815]. It is characterized by congenital microcephaly, psychomotor retardation, and seizures. |
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