6ilj

Cryo-EM structure of Echovirus 6 complexed with its attachment receptor CD55 at PH 5.5Cryo-EM structure of Echovirus 6 complexed with its attachment receptor CD55 at PH 5.5

Structural highlights 6ilj is a 5 chain structure with sequence from Echovirus e6 and Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: Gene: CD55, CR, DAF (HUMAN) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [DAF_HUMAN] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

spinqualitylabelsall models 6ilj, resolution 3.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image