1gzd

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Crystal structure of pig phosphoglucose isomeraseCrystal structure of pig phosphoglucose isomerase

Structural highlights

1gzd is a 1 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Glucose-6-phosphate isomerase, with EC number 5.3.1.9
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[G6PI_PIG] Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1gzd, resolution 2.50Å

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