4o1x

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Crystal structure of human thymidylate synthase double mutant C195S-Y202CCrystal structure of human thymidylate synthase double mutant C195S-Y202C

Structural highlights

4o1x is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
NonStd Res:,
Activity:Thymidylate synthase, with EC number 2.1.1.45
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TYSY_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.[1]

See Also

References

  1. ↑ Anderson DD, Quintero CM, Stover PJ. Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15163-8. doi:, 10.1073/pnas.1103623108. Epub 2011 Aug 26. PMID:21876188 doi:10.1073/pnas.1103623108

4o1x, resolution 2.32Å

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