6fmx

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IMISX-EP of W-PgpBIMISX-EP of W-PgpB

Structural highlights

6fmx is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:Phosphatidylglycerophosphatase, with EC number 3.1.3.27
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PGPB_BACSU] Catalyzes the dephosphorylation of phosphatidylglycerophosphate (PGP) to phosphatidylglycerol. Also has undecaprenyl pyrophosphate phosphatase activity, required for the biosynthesis of the lipid carrier undecaprenyl phosphate.[1]

References

  1. ↑ Ghachi ME, Howe N, Auger R, Lambion A, Guiseppi A, Delbrassine F, Manat G, Roure S, Peslier S, Sauvage E, Vogeley L, Rengifo-Gonzalez JC, Charlier P, Mengin-Lecreulx D, Foglino M, Touze T, Caffrey M, Kerff F. Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis. Cell Mol Life Sci. 2017 Feb 6. doi: 10.1007/s00018-017-2464-6. PMID:28168443 doi:http://dx.doi.org/10.1007/s00018-017-2464-6

6fmx, resolution 1.79Å

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