Crystal structure of human mitochondrial ClpP complex with acyldepsipeptide ADEP-28Crystal structure of human mitochondrial ClpP complex with acyldepsipeptide ADEP-28

Structural highlights

6bba is a 14 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
NonStd Res:, , ,
Activity:Endopeptidase Clp, with EC number 3.4.21.92
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CLPP_HUMAN] Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.

6bba, resolution 2.80Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA