Protein Rev

Function

Protein Rev (Rev) or regulator of virion is an HIV-1 accessory protein which overcomes the host cellular mechanism which blocks nuclear-cytoplasm export of incompletely processed mRNA^[1].

For more details see HIV and accessory proteins.

HIV-1 protein Rev (olive green) complex with anti-Rev antibody heavy chain (red) and light chain (aqua) (PDB code 5dhz)

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3D Structures of protein Rev3D Structures of protein Rev

Updated on 23-October-2017

3lph – Rev oligomerization and RNA-binding domains – HIV-1
1rpv – Rev RNA-binding domain – NMR
5dhz, 5dhv, 5dhx, 5dhy, 2xl7 – Rev + anti-Rev antibody
4pmi – Rev + Rev response element RNA
5dhx - Rev + 5eqz - Rev - Borellia burgdorferi

ReferencesReferences

↑ Cochrane A. HIV-1 Rev function and RNA nuclear-cytoplasmic export. Methods Mol Biol. 2014;1087:103-14. doi: 10.1007/978-1-62703-670-2_9. PMID:24158817 doi:http://dx.doi.org/10.1007/978-1-62703-670-2_9

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

[1] Cochrane A. HIV-1 Rev function and RNA nuclear-cytoplasmic export. Methods Mol Biol. 2014;1087:103-14. doi: 10.1007/978-1-62703-670-2_9. PMID:24158817 doi:http://dx.doi.org/10.1007/978-1-62703-670-2_9

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