Proteopedia

5tq2

Revision as of 22:15, 15 November 2017 by OCA (talk | contribs)

Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at GluN1 and GluN2ACrystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at GluN1 and GluN2A

Structural highlights

5tq2 is a 4 chain structure with sequence from African clawed frog, Buffalo rat and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Gene:grin1, NR1 (African clawed frog), Grin2a (Buffalo rat)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[NMDE1_RAT] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.

5tq2, resolution 3.29Å

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OCA
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