5ox2

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Crystal structure of thymoligase, a substrate-tailored peptiligase variantCrystal structure of thymoligase, a substrate-tailored peptiligase variant

Structural highlights

5ox2 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Subtilisin, with EC number 3.4.21.62
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[SUBT_BACAM] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides. Has a high substrate specificity to fibrin.[1]

References

  1. Peng Y, Huang Q, Zhang RH, Zhang YZ. Purification and characterization of a fibrinolytic enzyme produced by Bacillus amyloliquefaciens DC-4 screened from douchi, a traditional Chinese soybean food. Comp Biochem Physiol B Biochem Mol Biol. 2003 Jan;134(1):45-52. PMID:12524032

5ox2, resolution 2.24Å

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