Sequence

mutations with manual annotation; pathogenic; benign; not yet reviewed;
wild type Show which residues have mutations:


Phenylalanine hydroxylase is responsible for the conversion of phenylalanine to another amino acid, tyrosine. The enzyme works with a molecule called tetrahydrobiopterin (BH4) to carry out this chemical reaction. Tyrosine is used to make several types of hormones, certain chemicals that transmit signals in the brain (neurotransmitters), and a pigment called melanin, which gives hair and skin their color.

  • ToDo: cleanup elements between mutations display
  • ToDo: where are orange labels when allmutations?
  • ToDo: use ConSurf colouring on structure.
  • ToDo: Implement Template to render ALL mutations of a given model with ConSurf colouring.
  • ToDo: Check if model(s) structure loaded before displaying a mutation, to enable showing other structures and back to the sequence/model interaction. Currently model(s) structure loaded only on initial page loading.


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ReferencesReferences