Protein Rev

Revision as of 11:28, 9 January 2017 by Michal Harel (talk | contribs) (New page: <StructureSection load='5dhz' size='340' side='right' caption='Caption for this structure' scene=''> == Function == '''Protein Rev''' (Rev) or '''regulator of virion''' is an HIV-1 acce...)
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Function

Protein Rev (Rev) or regulator of virion is an HIV-1 accessory protein which overcomes the host cellular mechanism which blocks nuclear-cytoplasm export of incompletely processed mRNA[1].

For more details see HIV and accessory proteins.


Caption for this structure

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3D Structures of protein Rev3D Structures of protein Rev

Updated on 09-January-2017

3lph – Rev oligomerization and RNA-binding domains – HIV-1
1rpv – Rev RNA-binding domain – NMR
5dhz, 5dhv, 5dhx, 5dhy – Rev + anti-Rev antibody
4pmi – Rev + Rev response element RNA

ReferencesReferences

  1. Cochrane A. HIV-1 Rev function and RNA nuclear-cytoplasmic export. Methods Mol Biol. 2014;1087:103-14. doi: 10.1007/978-1-62703-670-2_9. PMID:24158817 doi:http://dx.doi.org/10.1007/978-1-62703-670-2_9

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Michal Harel