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5ti9

Revision as of 21:51, 26 October 2016 by OCA (talk | contribs)

Crystal structure of human TDO in complex with Trp and dioxygen, Northeast Structural Genomics Consortium Target HR6161Crystal structure of human TDO in complex with Trp and dioxygen, Northeast Structural Genomics Consortium Target HR6161

Structural highlights

5ti9 is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , ,
Activity:Tryptophan 2,3-dioxygenase, with EC number 1.13.11.11
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[T23O_HUMAN] Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity).

5ti9, resolution 2.50Å

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