4mso

X-ray crystal structure of a serine hydroxymethyl transferase in apo form from Burkholderia cenocepaciaX-ray crystal structure of a serine hydroxymethyl transferase in apo form from Burkholderia cenocepacia

Structural highlights 4mso is a 2 chain structure with sequence from Burcj. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: , Gene: glyA, glyA1, BceJ2315_31420, BCAL3197 (BURCJ) Activity: Glycine hydroxymethyltransferase, with EC number 2.1.2.1 Resources: FirstGlance, OCA, RCSB, PDBsum Function [B4ECY9_BURCJ] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051] See Also Serine hydroxymethyltransferase

spinqualitylabelsall models 4mso, resolution 1.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image