Cathepsin B in complex with the nitroxolineCathepsin B in complex with the nitroxoline

Structural highlights

3ai8 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:CTSB (HUMAN)
Activity:Cathepsin B, with EC number 3.4.22.1
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.

See Also

3ai8, resolution 2.11Å

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OCA