Structure of acetyl-Coenzyme A synthase Alpha subunit C-terminal domainStructure of acetyl-Coenzyme A synthase Alpha subunit C-terminal domain

Structural highlights

3s2x is a 2 chain structure with sequence from Moorella thermoacetica. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:CO-methylating acetyl-CoA synthase, with EC number 2.3.1.169
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[DCMA_MOOTH] The beta subunit generates CO from CO(2), while the alpha subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the alpha subunit by a corrinoid iron-sulfur protein.

See Also

3s2x, resolution 2.35Å

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OCA