3vpm

From Proteopedia
Revision as of 13:43, 25 December 2014 by OCA (talk | contribs)
Jump to navigation Jump to search

Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutantCrystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant

Structural highlights

3vpm is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:RR2, RRM2 (Homo sapiens)
Activity:Ribonucleoside-diphosphate reductase, with EC number 1.17.4.1
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[RIR2_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

See Also

3vpm, resolution 2.70Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA