Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator (N-(5-(azepan-1-ylsulfonyl)-2-methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide)Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator (N-(5-(azepan-1-ylsulfonyl)-2-methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide)

Structural highlights

5f91 is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Activity:Fumarate hydratase, with EC number 4.2.1.2
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[FUMC_MYCTO] Catalyzes the reversible addition of water to fumarate to give L-malate.

5f91, resolution 2.00Å

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OCA