Phenylpyruvate decarboxylase

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Template:STRUCTURE 2q5o

Phenylpyruvate decarboxylase (PPDC) catalyzes the conversion of phenylpyruvate to phenylacetaldehyde. PPDC participates in phenylalanine and tryptophan metabolism[1].


3D Structures of phenylpyruvate decarboxylase3D Structures of phenylpyruvate decarboxylase

2q5j, 2q5l – AbPPDC + deaza-ThDP derivative – Azospirillum brasilense

2q5o - AbPPDC + deaza-ThDP + phenylpyruvate

2q5q - AbPPDC + deaza-ThDP + phenylvalerate

ReferencesReferences

  1. Vuralhan Z, Morais MA, Tai SL, Piper MD, Pronk JT. Identification and characterization of phenylpyruvate decarboxylase genes in Saccharomyces cerevisiae. Appl Environ Microbiol. 2003 Aug;69(8):4534-41. PMID:12902239

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Michal Harel, Alexander Berchansky