Glucagon
FunctionFunction
Glucagon (GLC) is a hormone which raises blood glucose level. GLC causes the liver to convert glycogen to glucose. GLC effect is opposite to that of insulin[1]. See some details in User:Mary Ball/Glucagon.
RelevanceRelevance
Glucagon is injected in cases of severe glycemia[2]. Overdose of β blockers is treated with GLC. Epinephrin-resistant low blood pressure cases are treated with GLC. Pancreatic tumors may cause high levels of GLC.
3D Structures of glucagon3D Structures of glucagon
Updated on 06-March-2016
2g49 – hGLC preprotein residues 53-81+ insulin-degrading enzyme – human
1kx6, 2m5p, 2m5q – hGLC - NMR
1nau – hGLC (mutant) – NMR
1bh0 - hGLC (mutant)
1gcn - hGLC