3bgo

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Azide complex of Engineered Subtilisin SUBT_BACAMAzide complex of Engineered Subtilisin SUBT_BACAM

Structural highlights

3bgo is a 2 chain structure with sequence from Bacillus amyloliquefaciens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:apr (Bacillus amyloliquefaciens)
Activity:Subtilisin, with EC number 3.4.21.62
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[SUBT_BACAM] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides. Has a high substrate specificity to fibrin.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Peng Y, Huang Q, Zhang RH, Zhang YZ. Purification and characterization of a fibrinolytic enzyme produced by Bacillus amyloliquefaciens DC-4 screened from douchi, a traditional Chinese soybean food. Comp Biochem Physiol B Biochem Mol Biol. 2003 Jan;134(1):45-52. PMID:12524032

3bgo, resolution 1.80Å

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