3zlh

Structure of group A Streptococcal enolaseStructure of group A Streptococcal enolase

Structural highlights

3zlh is a 4 chain structure with sequence from Strp6. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Related:	3zlf, 3zlg
Activity:	Phosphopyruvate hydratase, with EC number 4.2.1.11
Resources:	FirstGlance, OCA, RCSB, PDBsum

Function

[ENO_STRP6] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.^[1]

References

↑ Pancholi V, Fischetti VA. alpha-enolase, a novel strong plasmin(ogen) binding protein on the surface of pathogenic streptococci. J Biol Chem. 1998 Jun 5;273(23):14503-15. PMID:9603964

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OCA

[1] Pancholi V, Fischetti VA. alpha-enolase, a novel strong plasmin(ogen) binding protein on the surface of pathogenic streptococci. J Biol Chem. 1998 Jun 5;273(23):14503-15. PMID:9603964

[1]

3zlh

Structure of group A Streptococcal enolaseStructure of group A Streptococcal enolase

Structural highlights

Function

See Also

References

Contents

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3zlh

Structure of group A Streptococcal enolaseStructure of group A Streptococcal enolase

Structural highlights

Function

See Also

References

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