1i4x
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STAPHYLOCOCCAL ENTEROTOXIN C2, MONOCLINIC FORM CRYSTALLIZED AT PH 8.0
OverviewOverview
The three-dimensional structure of staphylococcal enterotoxin C2 (SEC2), a, toxin as well as a superantigen, has been determined at various pH levels, from two different crystal forms, tetragonal (pH 5.0, 5.5, 6.0 and 6.5), and monoclinic (pH 8.0) at 100 and 293 K, respectively, by the, molecular-replacement method. Tetragonal crystals belong to space group, P4(3)2(1)2, with unit-cell parameters a = b = 42.68, c = 289.15 A (at pH, 5.0), and monoclinic crystals to space group P2(1), with unit-cell, parameters a = 43.3, b = 70.6, c = 42.2 A, beta = 90.3 degrees. SEC2, contains a zinc-binding motif, D+HExxH, and accordingly a Zn atom has been, identified. The coordination of the zinc ion suggests that it may be, catalytic zinc rather than structural, but there is so far no biological, ... [(full description)]
About this StructureAbout this Structure
1I4X is a [Single protein] structure of sequence from [Staphylococcus aureus] with ZN as [ligand]. Structure known Active Site: ZNB. Full crystallographic information is available from [OCA].
ReferenceReference
Structure of staphylococcal enterotoxin C2 at various pH levels., Kumaran D, Eswaramoorthy S, Furey W, Sax M, Swaminathan S, Acta Crystallogr D Biol Crystallogr. 2001 Sep;57(Pt 9):1270-5. Epub 2001, Aug 23. PMID:11526318
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