4en0

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Crystal structure of lightCrystal structure of light

Structural highlights

4en0 is a 3 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3ugn. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:HVEML, LIGHT, TNFSF14, UNQ391/PRO726 (Homo sapiens)
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[TNF14_HUMAN] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.

4en0, resolution 2.59Å

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OCA
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