4c6l

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Template:STRUCTURE 4c6l

Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 6.0Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 6.0

Template:ABSTRACT PUBMED 24332717

FunctionFunction

[PYR1_HUMAN] This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).

About this StructureAbout this Structure

4c6l is a 1 chain structure. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Grande-Garcia A, Lallous N, Diaz-Tejada C, Ramon-Maiques S. Structure, Functional Characterization, and Evolution of the Dihydroorotase Domain of Human CAD. Structure. 2013 Dec 10. pii: S0969-2126(13)00428-0. doi:, 10.1016/j.str.2013.10.016. PMID:24332717 doi:http://dx.doi.org/10.1016/j.str.2013.10.016

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