4njp
Proteolysis inside the membrane is a rate-governed reaction not Driven by substrate affinityProteolysis inside the membrane is a rate-governed reaction not Driven by substrate affinity
FunctionFunction
[GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.[1] [2]
About this StructureAbout this Structure
4njp is a 1 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Dickey SW, Baker RP, Cho S, Urban S. Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity. Cell. 2013 Dec 5;155(6):1270-81. doi: 10.1016/j.cell.2013.10.053. PMID:24315097 doi:http://dx.doi.org/10.1016/j.cell.2013.10.053
- ↑ Wu Z, Yan N, Feng L, Oberstein A, Yan H, Baker RP, Gu L, Jeffrey PD, Urban S, Shi Y. Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry. Nat Struct Mol Biol. 2006 Dec;13(12):1084-91. Epub 2006 Nov 10. PMID:17099694 doi:10.1038/nsmb1179
- ↑ Maegawa S, Ito K, Akiyama Y. Proteolytic action of GlpG, a rhomboid protease in the Escherichia coli cytoplasmic membrane. Biochemistry. 2005 Oct 18;44(41):13543-52. PMID:16216077 doi:10.1021/bi051363k