Crystal Structure of Recombinant Human Hexokinase Type I with 1,5-Anhydroglucitol 6-PhosphateCrystal Structure of Recombinant Human Hexokinase Type I with 1,5-Anhydroglucitol 6-Phosphate

Structural highlights

4fpb is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Gene:HK1 (Homo sapiens)
Activity:Hexokinase, with EC number 2.7.1.1
Resources:FirstGlance, OCA, RCSB, PDBsum

Disease

[HXK1_HUMAN] Defects in HK1 are the cause of hexokinase deficiency (HK deficiency) [MIM:235700]. HK deficiency is a rare autosomal recessive disease with nonspherocytic hemolytic anemia as the predominant clinical feature.

Function

See Also

4fpb, resolution 3.00Å

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OCA