HIV-1 Inhibitors with a Tertiary-Alcohol-containing Transition-State Mimic and various P2 and P1 prime SubstituentsHIV-1 Inhibitors with a Tertiary-Alcohol-containing Transition-State Mimic and various P2 and P1 prime Substituents

Structural highlights

2xye is a 2 chain structure with sequence from Hiv-1. Full crystallographic information is available from OCA.
Ligands:
Related:2vg7, 1har, 1ajv, 1hps, 1t7k, 1d4j, 1r0a, 1hpz, 2vg6, 1npa, 1qe1, 1hqe, 1ajx, 1tvr, 1ebk, 2ykn, 1s6p, 1ikv, 1bqm, 1w5y, 1hos, 1ikw, 1s6q, 3hvt, 1ec1, 1ec0, 2xyf, 1t05, 1d4i, 1rvq, 1meu, 1s9g, 2be2, 1hnv, 1rvr, 1ikx, 1w5w, 1qmc, 1iky, 1n6q, 1d4h, 1rvn, 1hbv, 1htf, 1rtd, 1ec2, 2hmi, 1w5v, 2uy0, 1sv5, 1hmv, 2bbb, 1s9e, 2x4u, 1n5y, 1dlo, 1heg, 1rvp, 1rvl, 1eet, 1dw6, 1yt9, 1w5x, 2b6a, 1hvu, 1htg, 1ebw, 1rdh, 2ban, 1j5o, 1eby, 1rvo, 1hvp, 1mes, 1ec3, 1hef, 1hih, 1hni, 1tv6, 2ykm, 1a9m, 2b5j, 1ebz, 1met, 1hys, 1t03, 1axa, 1mer, 1npw, 3tlh, 1suq, 2uxz, 1hvk, 1sbg, 1bqn, 1uwb, 2vg5, 1rvm, 1hte, 1hrh, 1npv, 1hqu
Activity:Glucokinase, with EC number 2.7.1.2
Resources:FirstGlance, OCA, RCSB, PDBsum

2xye, resolution 2.00Å

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OCA