Template:STRUCTURE 3flf

Thermolysin inhibitionThermolysin inhibition

Template:ABSTRACT PUBMED 20600625

FunctionFunction

[THER_BACTH] Extracellular zinc metalloprotease.

About this StructureAbout this Structure

3flf is a 1 chain structure with sequence from Bacillus thermoproteolyticus. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Englert L, Biela A, Zayed M, Heine A, Hangauer D, Klebe G. Displacement of disordered water molecules from hydrophobic pocket creates enthalpic signature: binding of phosphonamidate to the S(1)'-pocket of thermolysin. Biochim Biophys Acta. 2010 Nov;1800(11):1192-202. Epub 2010 Jul 1. PMID:20600625 doi:http://dx.doi.org/10.1016/j.bbagen.2010.06.009

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OCA