4chc
Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 2)Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 2)
Template:ABSTRACT PUBMED 24454773
FunctionFunction
[PA_THOGV] Initiates transcription by a unique cap-stealing mechanism that involves the cleavage of only the m(7)GpppAm structure from cellular hnRNAs.
About this StructureAbout this Structure
4chc is a 6 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Guilligay D, Kadlec J, Crepin T, Lunardi T, Bouvier D, Kochs G, Ruigrok RW, Cusack S. Comparative structural and functional analysis of orthomyxovirus polymerase cap-snatching domains. PLoS One. 2014 Jan 15;9(1):e84973. doi: 10.1371/journal.pone.0084973. eCollection, 2014 Jan 15. PMID:24454773 doi:http://dx.doi.org/10.1371/journal.pone.0084973