4b8r
Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK)Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK)
Template:ABSTRACT PUBMED 23818958
FunctionFunction
[GLKA_THELI] Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. Can also use CDP as the phosphoryl group donor and D-glucosamine and D-1,5-anhydroglucitol as the phosphoryl group acceptor.[1]
About this StructureAbout this Structure
4b8r is a 1 chain structure with sequence from Thermococcus litoralis. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Rivas-Pardo JA, Herrera-Morande A, Castro-Fernandez V, Fernandez FJ, Vega MC, Guixe V. Crystal Structure, SAXS and Kinetic Mechanism of Hyperthermophilic ADP-Dependent Glucokinase from Thermococcus litoralis Reveal a Conserved Mechanism for Catalysis. PLoS One. 2013 Jun 20;8(6):e66687. doi: 10.1371/journal.pone.0066687. Print 2013. PMID:23818958 doi:10.1371/journal.pone.0066687
- ↑ Koga S, Yoshioka I, Sakuraba H, Takahashi M, Sakasegawa S, Shimizu S, Ohshima T. Biochemical characterization, cloning, and sequencing of ADP-dependent (AMP-forming) glucokinase from two hyperthermophilic archaea, Pyrococcus furiosus and Thermococcus litoralis. J Biochem. 2000 Dec;128(6):1079-85. PMID:11098152