3t6b
Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 2.4 AngstromsStructure of human DPPIII in complex with the opioid peptide Tynorphin, at 2.4 Angstroms
FunctionFunction
[DPP3_HUMAN] Cleaves Arg-Arg-beta-naphthylamide.
About this StructureAbout this Structure
3t6b is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Bezerra GA, Dobrovetsky E, Viertlmayr R, Dong A, Binter A, Abramic M, Macheroux P, Dhe-Paganon S, Gruber K. Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6525-30. Epub 2012 Apr 9. PMID:22493238 doi:10.1073/pnas.1118005109