3k0a
Crystal structure of the phosphorylation-site mutant S431A of the KaiC circadian clock proteinCrystal structure of the phosphorylation-site mutant S431A of the KaiC circadian clock protein
Template:ABSTRACT PUBMED 19956664
FunctionFunction
[KAIC_SYNE7] Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction.[1][2]
About this StructureAbout this Structure
3k0a is a 6 chain structure with sequence from Synechococcus elongatus pcc 7942. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Pattanayek R, Mori T, Xu Y, Pattanayek S, Johnson CH, Egli M. Structures of KaiC circadian clock mutant proteins: a new phosphorylation site at T426 and mechanisms of kinase, ATPase and phosphatase. PLoS One. 2009 Nov 26;4(11):e7529. PMID:19956664 doi:10.1371/journal.pone.0007529
- ↑ Ishiura M, Kutsuna S, Aoki S, Iwasaki H, Andersson CR, Tanabe A, Golden SS, Johnson CH, Kondo T. Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria. Science. 1998 Sep 4;281(5382):1519-23. PMID:9727980
- ↑ Nakahira Y, Katayama M, Miyashita H, Kutsuna S, Iwasaki H, Oyama T, Kondo T. Global gene repression by KaiC as a master process of prokaryotic circadian system. Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):881-5. Epub 2004 Jan 6. PMID:14709675 doi:10.1073/pnas.0307411100
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OCACategories:
- Non-specific serine/threonine protein kinase
- Synechococcus elongatus pcc 7942
- Egli, M.
- Pattanayek, R.
- Pattanayek, S.
- Atp-binding
- Biological rhythm
- Circadian clock protein
- Dna-binding
- Hexamer
- Kaic
- Kinase
- Magnesium
- Metal-binding
- Nucleotide-binding
- Phosphoprotein
- Repressor
- Serine/threonine-protein kinase
- Transcription
- Transcription regulation
- Transferase